HEMOSTASIS

     ACTIVITIES

• Hemostasis is the first stage in wound healing that occurs immediately and can last for two days.
• When an injury occurs, the initial phase is always an outpouring of lymphatic fluid and blood.
• Blood vessels constrict to stop bleeding, called vasoconstriction.
• Your body activates its blood clotting system to prevent loss of blood.
  

INFLAMMATION. 

     ACTIVITIES

• The inflammatory phase begins with hemostasis and chemotaxis.
• Inflammation both controls bleeding and prevents infection.
• The fluid engorgement allows healing and repair cells to move to the site of the wound.
• During the inflammatory phase, damaged cells, pathogens, and bacteria are removed from the wound area.



PROLIFERATION

     ACTIVITIES

• The proliferative or granulation phase does not occur at a discrete time, but is ongoing all the time in the background.
• In the proliferation phase, the provisional wound matrix formed during hemostasis is replaced by granulation tissue.
• The fibroblasts have started to lay down new collagen and form the core of the wound to partially recover the structure and function of the wounded skin.

MATURATION

     ACTIVITIES

• Maturation, or remodeling, is the final phase of wound healing.
• This phase involves remodeling of collagen from type III to type I and the wound fully closes.
• Cellular activity reduces and the number of blood vessels in the wounded area regress and decrease.